Streamlining and accelerating Research & Development
Since 2009 designing better implants, faster and more cost-effective
97
FEA projects
39
Device models
53
Animal models
In the early phases of the design cycle, choosing which prototype to develop can be complicated.
There are a lot of unknowns to contend with.
FEops’ simulation technology helps fill in these blanks. It gives product developers digital simulations that let them evaluate the performance of multiple prototypes in terms of radial strength, crimpability, fatigue risk, and deployment behavior in validated virtual human and animal patients.
These virtual patients are provided by the customer or selected from the large FEops proprietary database, which includes both pathological and healthy patients.
“FEops simulation technology has been a valuable addition to our R&D group at every step of our device development, providing crucial anatomical insights, preventing fatigue issues in the early design of our device, assisting with the development of appropriate fatigue bench tests, and finally giving additional confidence for a successful Topaz TTVR first-in-human through their simulated preoperative implantations”
A testimonial, FEops simulation technology from initial design concepts to a successful First-in-human
R&D, from scarce pre-clinical data to FIM
Deployment
Simulation of expansion mechanisms
Do you want to know to what extent your device can be loaded,
expanded (and recaptured) ?
Virtual implants offer a more efficient way to explore design alternatives
With FEops simulation technology, design alternatives can be thoroughly investigated without being physically manufactured.
Braid for LAA closure
Mechanics of braided devices is accurately reproduced by FEA. Even unsheathing of complex shapes such LAA closure device can be captured by simulations at different stages.
Simulations of deployment (FEA) and flow diverting performance (CFD) of neurovascular devices provide an objective bench test to compare different devices under exactly the same conditions.
Neurovascular flow diverters stents
Proof-Of-Concept & Optimization
FEops simulation technology can investigate design alternatives without physical prototypes
Not sure which direction should your next design iteration take?
The number of design iterations and virtual patients that can be tested
with FEops HEARTguide™ is limitless.
By comparing the simulated treatment outcomes for different prototypes, it is possible to make precise design choices that target specific patient groups.
Discover the impact of various iterations of a prosthetic heart valve that has been virtually implanted into three different patients in this video.
► How the design of a TAVI device is gradually optimized to reduce paravalvular leak and conduction abnormalities.
Cyclic Loading and Fatigue
Simulations can reveal the pros and cons of a device
Interested to see how your (future) device will interact with validated virtual human and animal heart models?
Simulations provide in-vivo fatigue safety factor, testing impact of different implantation depths/angles on the in-vivo cyclic loading. 3D contour plots and diagrams will identify hotspots of potential (fretting) fatigue failure.
By combining preoperative 4D CT data and device data FEops can investigate the performance of your cardiac device under realistic (cyclic) loading conditions and in different disease states.
First-in-human Study
FEops’ simulation technology can predict outcomes in both humans and animals.
Did you prepare your animal test or your compassionate case?
Simulations will show you upfront risks of device-related failure
FEops can predict device instability, reveal sub-optimal functionality, and assess the risk of fatigue.
After iterative comparison to post-op CT scans simulations provide quantitative criteria for patient selection.