Going Beyond Traditional Procedure Planning for Structural Heart Interventions

FEops HEARTguide™ is a unique, stand-alone solution. It combines predictive simulation with AI-based anatomical measurements to deliver results that are easy to integrate into a clinical workflow.

The FEops HEARTguide™ 3-step process
1. Patient CT-scan upload
2. FEops HEARTguide™ analysis
3. Centrally accessible insights*

Plan with more confidence

Select the optimal device size and implant position using unmatched predictive simulation.

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Assess device apposition and frame deformation.

Improved efficiency and outcomes

Clinically proven results.

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PREDICT-LAA study
15% reduction in the total number of closure devices used.
Twofold increase in procedural success with single device and deployment (+90 days).

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PRECISE-TAVI study
35% of pre-procedural decisions were changed, resulting in favorable clinical outcomes.

Save time with
AI-based anatomical analysis

Fast, accurate anatomical analysis with semi-automatic identification and measurements of anatomical landmarks.

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Assess implant size and position options easily with the 3D viewer

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Take full control using the options for manual measurements

Save Time with AI-based Anatomical Analysis

FEops HEARTguide™ has been developed for fast and accurate anatomical analysis. It includes semi-automatic identification and measurement of anatomical landmarks. The DICOM interface allows cardiologists, medical care providers, researchers, and others to easily conduct a full review of a patient’s anatomical landmarks.

Key benefits:

Semi-automatic identification and measurement of anatomical landmarks.
Users have full control thanks to the manual measurement options.
Interactive analysis between 2D and 3D Viewer for each landmark.

All the necessary tools close at hand
FEops HEARTguide™ provides general functionalities such as:
– Segmentation of cardiovascular structures.
– Visualization and image reconstruction techniques: 2D review and MPR.
– Tools for taking measurements and making annotations.

Our Solutions

FEops HEARTguide™ is a procedure planning platform that has been specifically developed for interventional cardiologists. It enables them to plan percutaneous procedures quickly and accurately. Multiple workflows have been developed to suit different situations.

Clinical workflows in Structural heart*

LAAO*

TAVI*

More exciting innovations in the FEops pipeline

TMVR**

Collaborative platform

FEops HEARTguide, cloud-based planning platform, offers secure access from anywhere at any time to automated anatomical analysis and predictive planning for Structural Heart interventions. This new release gives you now the possibility to grant secure access to other FEops HEARTguide users outside your organization, for one or multiple of your cases. This new feature will make it easier and secure your case sharing with peers and industry partners and transforms FEops HEARTguide into a unique collaborative platform.

Key benefits:

Case sharing with peers and industry partners *
Manual or automatic
e.g. proctoring, congress etc.

(*) option to revoke access at any time.

Left Atrial Appendage Occlusions

Improved efficiency and outcomes of LAAO procedures¹

Get unique insights and make LAAO procedures more predictable with FEops HEARTguide™

FEops HEARTguide™ enables a clear assessment of a patient’s anatomy. The software provides a segmentation of the left side of the heart with semi-automatic identification and measurement of anatomical landmarks. The 3D Model can be rotated to enable detailed assessment of left atrial appendage (LAA) morphology. It is also possible to evaluate different device sizes and positioning options using predicted device apposition, frame deformation and compression rate of the simulated LAA occluder. And physicians can select the optimal device size and implant position for a patient by using predictive simulation to see how a specific LAA occluder will interact with that patient’s unique anatomy.

Key benefits:
- Predict device apposition, frame deformation and compression rate.
- Select the optimal device size and implant position for a specific patient.
- C-arm angulation with pre-defined views: optimal projection and lateral-apical for TSP guidance.
- Improve procedural success rates by using one device and one deployment¹

¹ PREDICT-LAA , J Am Coll Cardiol Intv. Feb 22, 2023. Epublished DOI: 10.1016/j.jcin.2023.01.008

Transcatheter Aortic Valve Implantation

Understand options for future valve-in-valve procedures*

To address the increasing needs on TAVI lifetime management, the new release of FEops HEARTguide™ provides now for each simulation future redo-TAVI options with coronary access insights and a qualitative evaluation of the leaflet overhang.

Plan even your most challenging TAVI cases with confidence

Next to lifetime management options, FEops HEARTguide™ will provide for each simulation of the index TAVI the following output :

The skirt apposition will provide valuable insight in the sealing of the device to the anatomy, and the contact area indication will provide a qualitative insight on the contact of the device in the region of the conduction system.
Aorta and mitral calcifications are now also visible in the simulation view (undeformed).

Updated TAVI simulation output

Key benefits
- Assess the index valve size and position to ensure it accommodates future procedures, enabling effective lifetime management.
- Assess potential complications² for different device sizes and positions like challenging coronary access.
- Most appropriate treatment modality for patients with Bicuspid Aortic Valve (BAV) .³
- Select proper angulation with pre-defined views: “Cusp Overlap” view and “Three-cusp” view.

²Hokken T. - Van Mieghem N. et al. Computed Tomography-Derived Predictive Simulations of Transcatheter Aortic Valve Replacement in Challenging Anatomies. CRT-700.26 JACC Cardiovascular Interventions, February 2022
³Dowling C. et al, Ongoing experience with patient-specific computer simulation of transcatheter aortic valve replacement in bicuspid aortic valve. https://doi.org/10.1016/j.carrev.2023.01.015. CardiovascularRevascularizationMedicine, In Press, Jan 2023

Transcatheter Mitral Valve Replacement

Early evidence supports the use of FEops simulation technology in TMVR

Neo-left ventricle outflow tract (neo-LVOT) assessment
● Early research² supports the use of FEops simulation technology in transcatheter mitral valve replacement (TMVR).
● FEops HEARTguide provides a finite element simulation based on segmentation of the CT scan. This enables it to calculate the neo-LVOT area at various heights of deployment.

Transcatheter mitral valve replacement in mitral annulus calcification (MAC)
● Computer simulation may have the potential to improve patient selection for transcatheter mitral valve replacement in the presence of significant MAC.³

¹FEops HEARTguide is currently not indicated for clinical use in TMVR
²Chehab et al, JACC State-of-the-Art Review VOL. 80, NO. 7, 2022 Management of Patients With Severe Mitral Annular Calcification
³Karady J, et al, JCCT ref 1052 DOI: 10.1016/j.jcct.2017.12.007Transcatheter mitral valve replacement in mitral annulus calcification – “The art of computer simulation”

*In EU, UK, Canada and Australia, FEops HEARTguide™ is available for AI-enabled anatomical analysis and computer simulation with indication for use in TAVI and LAAO. In USA, FEops HEARTguide ™ is available for AI-enabled anatomical analysis with indication for use in TAVI and LAAO and for computer simulation in LAAo with WATCHMAN™, WATCHMAN™FLX, Amplatzer™ Amulet™.
**FEops HEARTguide is currently not indicated for clinical use in TMVR